How can I get Erivedge?
Genentech Access Solutions is dedicated to helping you understand your insurance coverage and assistance options. This can help you get the Genentech medicine your doctor prescribed. There may be assistance for people taking Genentech medicines who have:
- A commercial insurance plan (such as one you get through your employer or through a Health Insurance Marketplace like HealthCare.gov)
- A public insurance plan (such as Medicare or Medicaid)
- No insurance
To find out which of our assistance options is right for you, visit Genentech-Access.com/Erivedge/patients or call (888) 249-4918.
How should I take Erivedge?
It’s very important to make sure you take Erivedge capsule exactly as your doctor tells you.
Here are a few things to remember:
- Take 1 capsule every day, with or without food
- Be sure to swallow the capsule whole
- Do not open or crush the capsule
If you happen to miss a dose:
- Skip the missed dose and take your next scheduled dose
How long you should take Erivedge:
Talk to your doctor about how long you should take Erivedge. It’s recommended that you continue taking Erivedge as long as it’s working for you and your side effects are tolerable.
In a clinical study of 104 adults with advanced BCC, 96 of whom were evaluated for overall response rate, half of the patients took Erivedge for more than 10 months, and half took Erivedge for less than 10 months. Patients stayed on Erivedge anywhere from 3 weeks to 19 months.
Important Safety Information and Indication
Erivedge® (vismodegib) capsule is a prescription medicine used to treat adults with a type of skin cancer, called basal cell carcinoma, that has spread to other parts of the body or that has come back after surgery or that your healthcare provider decides cannot be treated with surgery or radiation.
It is not known if Erivedge is safe and effective in children.
Serious Side Effects
Erivedge can cause your baby to die before it is born (be stillborn) or cause your baby to have severe birth defects.
Important Safety Information
What is the most important information I should know about Erivedge?
- Erivedge can cause your baby to die before it is born (be stillborn) or cause your baby to have severe birth defects
For females who can become pregnant:
- You should talk with your healthcare provider about the risks of Erivedge to your unborn child
- Your healthcare provider will do a pregnancy test within 7 days before you start taking Erivedge
- In order to avoid pregnancy, you should use birth control during treatment and for 24 months after your final dose of Erivedge. Talk with your healthcare provider about what birth control method is right for you during this time
- Talk to your healthcare provider right away if you have unprotected sex or if you think that your birth control has failed
- Tell your healthcare provider right away if you become pregnant or think that you may be pregnant
- Erivedge is present in semen. Do not donate semen while you are taking Erivedge and for 3 months after your final dose
- You should always use a condom, even if you have had a vasectomy, during sex with female partners who are pregnant or who are able to become pregnant, during treatment with Erivedge, and for 3 months after your final dose to protect your female partner from being exposed to Erivedge
- Tell your healthcare provider right away if your partner becomes pregnant or thinks she is pregnant while you are taking Erivedge
Exposure to Erivedge during pregnancy:
There is a Pregnancy Exposure Registry for females taking Erivedge who become pregnant. The purpose of this registry is to monitor the health of you and your unborn baby. If you think that you or your female partner may have been exposed to Erivedge during pregnancy, talk to your healthcare provider right away. If you become pregnant during treatment with Erivedge, you or your healthcare provider should report your pregnancy to Genentech at (888) 835-2555.
What should I tell my healthcare provider before taking Erivedge?
- If you are pregnant or plan to become pregnant
- If you are breastfeeding or plan to breastfeed. It is not known if Erivedge passes into your breast milk. You should not breastfeed during treatment and for 24 months after your final dose of Erivedge. Talk to your healthcare provider about the best way to feed your baby during this time
- About all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements
What should I avoid while taking Erivedge?
- Do not donate blood or blood products while you are taking Erivedge and for 24 months after your final dose
- Do not donate semen while you are taking Erivedge and for 3 months after your final dose
What are the possible side effects of Erivedge?
- Bone growth problems. Bone growth problems have happened in children who have been exposed to Erivedge. These problems may continue even after stopping treatment with Erivedge
- The most common side effects of Erivedge are:
- Muscle spasms
- Hair loss
- Change in how things taste or loss of taste
- Weight loss
- Decreased appetite
- Joint pain
Erivedge can cause absence of menstrual periods (amenorrhea) in females who are able to become pregnant. It is not known if amenorrhea is permanent. Talk to your healthcare provider if you have concerns about fertility.
These are not all of the possible side effects of Erivedge. Because everyone is different, it is not possible to predict what side effects any one person will have or how severe they may be. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555.